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Medication

Midazolam in US EMS protocols

231protocols
193named agencies
51states and regions
31indications
2,685dose entries
100% of 2,685machine-parsed

Includes 4 agencies outside the US.

IndicationSpread: box is the middle half, dot means most agreeRange
ACS / chest pain Adult2.5 to 5 mg median 2.5, n=5
Agitation Adult2 to 10 mg median 3.75, n=124
Adult, weight-based0.05 to 0.2 mg/kg median 0.1, n=17
Pediatric1 to 2.5 mg median 2.5, n=6
Pediatric, weight-based0.05 to 0.3 mg/kg median 0.1, n=79
Bradycardia Adult1 to 5 mg median 2.5, n=11
Pediatric, weight-based0.05 to 0.2 mg/kg median 0.1, n=5
Eclampsia / pre-eclampsia Adult2 to 10 mg median 6, n=21
Hyperactive delirium Adult2 to 10 mg median 5, n=34
Pediatric, weight-based0.1 to 0.2 mg/kg median 0.1, n=17
Hyperthermia Pediatric, weight-based0.1 to 0.2 mg/kg median 0.1, n=5
Nerve agent exposure Adult3.5 to 10 mg median 5, n=7
Pediatric, weight-based0.1 to 0.2 mg/kg median 0.2, n=6
Other Adult1 to 5 mg median 2.5, n=139
Adult, weight-based0.05 to 0.2 mg/kg median 0.1, n=40
Pediatric2 to 5 mg median 3.5, n=9
Pediatric, weight-based0.05 to 0.2 mg/kg median 0.1, n=117
Mild to moderate pain Adult1 to 5 mg median 2, n=13
Pediatric, weight-based0.05 to 0.1 mg/kg median 0.1, n=6
Post-intubation sedation Adult1 to 5 mg median 2.5, n=43
Adult, weight-based0.05 to 0.1 mg/kg median 0.05, n=17
Pediatric, weight-based0.05 to 0.3 mg/kg median 0.1, n=34
Procedural sedation Adult1 to 5 mg median 2, n=144
Adult, weight-basedMost use 0.1 mg/kg range 0.05 to 0.2 mg/kg, n=14
Pediatric, weight-basedMost use 0.1 mg/kg range 0.05 to 0.2 mg/kg, n=90
RSI induction Adult1 to 5 mg median 2.5, n=32
Adult, weight-based0.1 to 0.2 mg/kg median 0.1, n=11
Pediatric, weight-basedMost use 0.1 mg/kg range 0.05 to 0.2 mg/kg, n=23
Seizure Adult2 to 10 mg median 5, n=165
Adult, weight-based0.1 to 0.2 mg/kg median 0.15, n=32
Pediatric2.5 to 5 mg median 3.75, n=5
Pediatric, weight-based0.1 to 0.4 mg/kg median 0.15, n=176
Status epilepticus Adult2 to 10 mg median 5, n=16
Pediatric, weight-based0.1 to 0.2 mg/kg median 0.15, n=16
Narrow-complex tachycardia Adult1 to 3.75 mg median 2.5, n=12
Pediatric, weight-based0.05 to 0.2 mg/kg median 0.0875, n=6
Wide-complex tachycardia AdultMost use 2.5 mg range 2 to 2.5 mg, n=6

Too few protocols to chart yet (protocols in brackets): Atrial fibrillation with RVR (2), Alcohol withdrawal (5), Asthma / bronchospasm (1), Beta-blocker / calcium-channel-blocker overdose (1), Burns (2), Cardiac arrest (4), CHF / pulmonary edema (4), COPD (1), Dystonic reaction (5), Hypothermia (1), Nausea / vomiting (2), Organophosphate poisoning (2), Post-ROSC care (4), SVT (2), VF / pulseless VT (1)

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Named agencies with a page189

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Cite this

United States EMS Protocol Census, Midazolam: n=231 protocols from 193 named agencies / 51 states, as of 2026-10-31

MethodologyData licenseStudy your own protocol in the app

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.