A–C Acetaminophen, Adenosine, Albuterol, Amiodarone, Aspirin, Atropine, Buprenorphine, Calcium Chloride, Calcium Gluconate, Cetirizine10

Acetaminophen

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	peds	15 mg/kg	IV/PO	not captured	standing	page 37
Mild to moderate pain	adult	650–1000 mg	PO	not captured	standing	page 37
Mild to moderate pain	adult	650–1000 mg	IV	not captured	standing	page 37
Mild to moderate pain	peds	15 mg/kg	PO	not captured	standing	page 37
Mild to moderate pain	peds	15 mg/kg	IV	not captured	standing	page 37

Adenosine

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	6 mg	IV	not captured	standing	page 68
Other	peds	0.1 mg/kg	IV/IO	not captured	standing	page 67
SVT	adult	6 mg	IV/IO	not captured	standing	pages 66, 67
SVT	peds	0.1 mg/kg	IV/IO	not captured	standing	pages 66, 67
Wide-complex tachycardia	adult	6 mg	IV	not captured	standing	page 68

Albuterol

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	adult	2.5 mg	NEB	not captured	standing	pages 16, 17
Anaphylaxis	peds	1.25 mg	NEB	not captured	standing	pages 16, 17
Asthma / bronchospasm	adult	2.5–3 mg	NEB	not captured	standing	pages 23, 25
Asthma / bronchospasm	peds	1.25 mg	NEB	not captured	standing	pages 23, 25
Other	peds	2.5 mg	NEB	not captured	standing	page 17

Amiodarone

Indication	Population	Dose	Route	Repeat	Standing	Source
Atrial fibrillation with RVR	adult	150 mg	IV/IO	not captured	standing	pages 56, 66
Other	adult	150 mg	IV/IO	not captured	standing	page 65
Other	adult	150 mg	IV/IO	not captured	standing	page 56
Other	adult	150 mg	IV/IO	not captured	standing	page 68
Wide-complex tachycardia	adult	150 mg	IV/IO	not captured	standing	page 68
VF / pulseless VT	adult	300 mg	IV/IO	not captured	standing	pages 61, 62
VF / pulseless VT	adult	300 mg	IV/IO	not captured	standing	pages 61, 62
VF / pulseless VT	peds	5 mg/kg	IV/IO	not captured	standing	pages 61, 62
VF / pulseless VT	peds	5 mg/kg	IV/IO	not captured	standing	pages 61, 62

Aspirin

Indication	Population	Dose	Route	Repeat	Standing	Source
ACS / chest pain	adult	324–325 mg	PO	not captured	standing	pages 53, 162
ACS / chest pain	adult	324–325 mg	not captured	not captured	standing	page 53

Atropine

Indication	Population	Dose	Route	Repeat	Standing	Source
Bradycardia	adult	1 mg	IV/IO	not captured	standing	pages 57, 58
Bradycardia	peds	0.02 mg/kg	IV/IO	not captured	standing	pages 57, 58
Cardiac arrest	adult	1 mg	IV/IO	not captured	standing	pages 59, 60
Cardiac arrest	peds	0.02 mg/kg	IV/IO	not captured	standing	pages 59, 60
Organophosphate poisoning	adult	2 mg	IV/IO	not captured	standing	page 29
Other	adult	1 mg	IV/IO	not captured	standing	page 57
Other	adult	2 mg	IM	not captured	standing	page 30
Other	adult	2 mg	IM	not captured	standing	page 30
Other	adult	2–5 mg	IV/IO	not captured	standing	page 38
Other	peds	0.02 mg/kg	IV/IO	not captured	standing	page 38
Other	peds	0.3–0.75 mg	not captured	not captured	standing	page 31
Other	peds	0.5–1.25 mg	not captured	not captured	standing	page 31
Other	peds	0.5 mg	IM	not captured	standing	page 31
Other	peds	0.6–1.5 mg	not captured	not captured	standing	page 31
Other	peds	0.7–1.75 mg	not captured	not captured	standing	page 31
Other	peds	1.5 mg	IM	not captured	standing	page 31

Buprenorphine

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	16 mg	SL	not captured	standing	page 105

Calcium Chloride

Indication	Population	Dose	Route	Repeat	Standing	Source
Hyperkalemia	adult	1 g	IV/IO	not captured	standing	pages 49, 59, 142
Hyperkalemia	peds	20 mg/kg	IV/IO	not captured	standing	pages 49, 59, 142
Other	adult	1 g	IV/IO	not captured	standing	page 142
Other	peds	20 mg/kg	IV/IO	not captured	standing	pages 32, 57
Other	peds	20 mg/kg	IV/IO	not captured	standing	page 142

Calcium Gluconate

Indication	Population	Dose	Route	Repeat	Standing	Source
Eclampsia / pre-eclampsia	peds	20 mg/kg	IV/IO	not captured	standing	page 32
Hyperkalemia	adult	1 g	IV	not captured	standing	page 49
Hyperkalemia	peds	20 mg/kg	IV	not captured	standing	page 49
Other	adult	1 g	IV/IO	not captured	standing	pages 38, 57
Other	adult	1 g	IV/IO	not captured	standing	page 142
Other	adult	1 g	IV	not captured	standing	page 110
Other	peds	20 mg/kg	IV/IO	not captured	standing	pages 38, 57
Other	peds	20 mg/kg	IV/IO	not captured	standing	page 142

Cetirizine

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	adult	10 mg	PO/ODT	not captured	standing	pages 16, 17
Anaphylaxis	peds	2.5 mg	PO/ODT	not captured	standing	pages 16, 17
Other	adult	10 mg	PO/ODT	not captured	standing	pages 16, 17
Other	adult	10 mg	IV	not captured	standing	page 16
Other	peds	10 mg	PO/ODT	not captured	standing	pages 16, 17
Other	peds	5 mg	PO/ODT	not captured	standing	page 17

D–F Dextrose, Diazepam, Diltiazem, Diphenhydramine, Dopamine, Epinephrine, Epinephrine-Surfactant, Epinephrine-Surfactant Nasal Preparation, Fentanyl, Furosemide10

Dextrose

Indication	Population	Dose	Route	Repeat	Standing	Source
Hyperkalemia	adult	25 g	IV/IO	not captured	standing	page 142
Hyperkalemia	peds	0.5 g/kg	IV/IO	not captured	standing	page 142
Other	adult	12.5 g	IV/IO	not captured	standing	pages 18, 19
Other	peds	0.5 g/kg	IV/IO	not captured	standing	pages 18, 19

Diazepam

Indication	Population	Dose	Route	Repeat	Standing	Source
Organophosphate poisoning	adult	10 mg	IM	not captured	standing	pages 29, 30

Diltiazem

Indication	Population	Dose	Route	Repeat	Standing	Source
Atrial fibrillation with RVR	adult	0.25 mg/kg	IV/IO	not captured	standing	pages 56, 66
Atrial fibrillation with RVR	adult	0.25 mg/kg	IV/IO	not captured	standing	pages 56, 66
SVT	adult	0.25 mg/kg	IV/IO	not captured	standing	pages 56, 66

Diphenhydramine

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	50 mg	IV	not captured	standing	page 158
Other	peds	50 mg	IV	not captured	standing	page 158

Dopamine

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	adult	2–20 mcg/kg	IV/IO	not captured	standing	page 16
Bradycardia	adult	2–20 mcg/kg	IV/IO	not captured	standing	page 57
Hypotension / shock	adult	2–20 mcg/kg	IV/IO	not captured	standing	pages 42, 44, 45, 65
Hypotension / shock	peds	2–20 mcg/kg	IV/IO	not captured	standing	pages 42, 44, 45, 65
Sepsis	adult	2–20 mcg/kg	IV/IO	not captured	standing	pages 45, 65

Epinephrine

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	adult	0.3 mg	IM	not captured	standing	pages 16, 17
Anaphylaxis	peds	0.15 mg	IM	not captured	standing	pages 16, 17
Anaphylaxis	peds	0.3 mg	IM	not captured	standing	page 17
Bradycardia	adult	2–10 mcg	IV/IO	not captured	standing	pages 57, 58
Bradycardia	peds	0.01 mg/kg	IV/IO	not captured	standing	pages 57, 58
Bradycardia	peds	0.01–0.03 mg/kg	IV/IO	not captured	standing	pages 57, 58
Cardiac arrest	adult	1 mg	IV/IO	not captured	standing	pages 59, 60, 61, 62
Cardiac arrest	peds	0.01 mg/kg	IV/IO	not captured	standing	pages 59, 60, 61, 62
Other	adult	0.3 mg	IM	not captured	standing	page 16
Other	peds	0.01 mg/kg	IV/IO	not captured	standing	pages 59, 60
Other	peds	0.15 mg	IM	not captured	standing	page 16
Sepsis	peds	0.1 mcg/kg	IV/IO	not captured	standing	pages 45, 46

Epinephrine-Surfactant

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	peds	1 spray	IN	not captured	standing	page 17
Other	adult	1 spray	IN	not captured	standing	pages 16, 17
Other	peds	1 spray	IN	not captured	standing	pages 16, 17

Epinephrine-Surfactant Nasal Preparation

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	adult	1 spray	IN	not captured	standing	pages 16, 17
Anaphylaxis	peds	1 spray	IN	not captured	standing	pages 16, 17
Other	peds	1 spray	IN	not captured	standing	page 17

Fentanyl

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	0.5–1 mcg/kg	IV/IO	not captured	standing	page 89
Other	adult	0.5–1 mcg/kg	IV/IO	not captured	standing	page 89
Other	adult	1 mcg/kg	IV/IO/IM/IN	not captured	standing	page 37
Other	adult	50 mcg	IV/IO/IM/IN	not captured	standing	page 64
Other	peds	1 mcg/kg	IV/IO/IM/IN	not captured	standing	page 37
Mild to moderate pain	adult	1 mcg/kg	IV/IO/IM/IN	not captured	standing	pages 37, 162
Mild to moderate pain	peds	1 mcg/kg	IV/IO/IM/IN	not captured	standing	pages 37, 162
Procedural sedation	adult	1 mcg/kg	IV/IO/IM/IN	not captured	standing	page 124

Furosemide

Indication	Population	Dose	Route	Repeat	Standing	Source
CHF / pulmonary edema	adult	20–40 mg	IV/IO	not captured	standing	page 63
Hyperkalemia	adult	0.5–1 mg/kg	IV/IO	not captured	standing	page 142
Other	adult	0.5–1 mg/kg	IV/IO	not captured	standing	page 142
Other	adult	40 mg	IV/IO	not captured	standing	page 38
Other	adult	40 mg	IV	not captured	standing	page 158
Other	peds	0.5 mg/kg	IV/IO	not captured	standing	page 38
Other	peds	0.5–1 mg/kg	IV/IO	not captured	standing	page 142

G–L Glucagon, Haloperidol, Hydrocortisone, Hydroxocobalamin, Hypertonic Saline, Ibuprofen, Insulin, Ipratropium, Ketamine, Ketorolac, Lidocaine, Low Titer Type O+ Whole Blood, Low Titer Type O+ Whole Blood Or Packed Red Blood Cells13

Glucagon

Indication	Population	Dose	Route	Repeat	Standing	Source
Beta-blocker / calcium-channel-blocker overdose	adult	1–5 mg	IV/IO/IM	not captured	standing	page 38
Beta-blocker / calcium-channel-blocker overdose	adult	1–5 mg	IV/IO/IM	not captured	standing	page 38
Beta-blocker / calcium-channel-blocker overdose	peds	0.5 mg	IV/IO/IM	not captured	standing	page 38
Hypoglycemia	adult	1 mg	IM/IN	not captured	standing	pages 18, 19, 96
Hypoglycemia	adult	1 mg	IV/IO/IM/IN	not captured	standing	pages 18, 96
Hypoglycemia	peds	0.1 mg/kg	IV/IO/IM/IN	not captured	standing	page 19
Hypoglycemia	peds	0.5 mg	IM/IN	not captured	standing	pages 19, 96
Hypoglycemia	peds	0.5 mg	IM/IN	not captured	standing	pages 18, 19, 96
Hypoglycemia	peds	1 mg	IM/IN	not captured	standing	pages 19, 96

Haloperidol

Indication	Population	Dose	Route	Repeat	Standing	Source
Agitation	adult	5 mg	IM	not captured	standing	page 21

Hydrocortisone

Indication	Population	Dose	Route	Repeat	Standing	Source
Adrenal crisis	adult	100 mg	IV/IO/IM	not captured	standing	page 15
Adrenal crisis	peds	2 mg/kg	IV/IO/IM	not captured	standing	page 15
Anaphylaxis	adult	100 mg	IV/IO/IM	not captured	standing	pages 16, 17
Anaphylaxis	peds	2 mg/kg	IV/IO/IM	not captured	standing	pages 16, 17
Asthma / bronchospasm	adult	100 mg	IV/IO/IM	not captured	standing	pages 23, 26
Asthma / bronchospasm	peds	2 mg/kg	IV/IO/IM	not captured	standing	pages 23, 26
Other	adult	100 mg	IV/IO/IM	not captured	standing	pages 23, 26
Other	peds	2 mg	IV/IO/IM	not captured	standing	pages 23, 26

Hydroxocobalamin

Indication	Population	Dose	Route	Repeat	Standing	Source
Cyanide poisoning	adult	5 g	IV/IO	not captured	standing	pages 38, 70
Cyanide poisoning	peds	70 mg/kg	IV/IO	not captured	standing	pages 38, 70
Other	adult	5 g	IV/IO	not captured	standing	page 70
Other	peds	70 mg/kg	IV/IO	not captured	standing	page 70

Hypertonic Saline

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	peds	3 mL/kg	IV	not captured	standing	page 74

Ibuprofen

Indication	Population	Dose	Route	Repeat	Standing	Source
Mild to moderate pain	adult	600 mg	PO	not captured	standing	page 37
Mild to moderate pain	peds	10 mg/kg	PO	not captured	standing	page 37

Insulin

Indication	Population	Dose	Route	Repeat	Standing	Source
Hyperkalemia	adult	10 unit	IV/IO	not captured	standing	page 142
Hyperkalemia	peds	0.1 unit/kg	IV/IO	not captured	standing	page 142
Other	adult	10 unit	IV/IO	not captured	standing	page 142
Other	peds	0.1 unit/kg	IV/IO	not captured	standing	page 142

Ipratropium

Indication	Population	Dose	Route	Repeat	Standing	Source
Asthma / bronchospasm	adult	500 mcg	NEB	not captured	standing	pages 23, 25
Asthma / bronchospasm	peds	250–500 mcg	NEB	not captured	standing	pages 23, 25
Other	peds	250 mcg	NEB	not captured	standing	page 25
Other	peds	500 mcg	NEB	not captured	standing	page 25

Ketamine

Indication	Population	Dose	Route	Repeat	Standing	Source
Agitation	adult	4 mg/kg	IM	not captured	standing	page 21
Other	adult	1 mg/kg	IM	not captured	standing	page 124
Other	adult	1–2 mg/kg	IV/IO	not captured	standing	page 89
Other	adult	1–2 mg/kg	IV/IO	not captured	standing	page 89
Other	adult	50 mg	IM	not captured	standing	page 145
Other	peds	0.4 mg/kg	IM	not captured	standing	page 145
Mild to moderate pain	adult	0.15 mg/kg	IV/IO	not captured	standing	page 37
Mild to moderate pain	adult	0.3 mg/kg	IM/IN	not captured	standing	page 37

Ketorolac

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	peds	0.5 mg/kg	IV/IM	not captured	standing	page 37
Mild to moderate pain	adult	15 mg	IV	not captured	standing	page 37
Mild to moderate pain	adult	30 mg	IM	not captured	standing	page 37
Mild to moderate pain	peds	0.5 mg/kg	IV	not captured	standing	page 37
Mild to moderate pain	peds	0.5 mg/kg	IM	not captured	standing	page 37

Lidocaine

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	1–1.5 mg/kg	IV/IO	not captured	standing	page 68
Other	adult	1–1.5 mg/kg	IV/IO	not captured	standing	page 65
Mild to moderate pain	adult	40 mg	IO	not captured	standing	page 7
Mild to moderate pain	adult	40 mg	IO	not captured	standing	page 7
Mild to moderate pain	peds	1 mg/kg	IO	not captured	standing	page 7
Mild to moderate pain	peds	1 mg/kg	IO	not captured	standing	page 7
VF / pulseless VT	adult	1.5 mg/kg	IV/IO	not captured	standing	page 61

Low Titer Type O+ Whole Blood

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	1 unit	IV	not captured	standing	pages 110, 111
Other	peds	10 mL/kg	IV	not captured	standing	pages 110, 111

Low Titer Type O+ Whole Blood Or Packed Red Blood Cells

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	1 unit	IV	not captured	standing	pages 110, 111
Other	peds	10 mL/kg	IV	not captured	standing	pages 110, 111

M–O Magnesium Sulfate, Methylprednisolone, Metoprolol, Midazolam, Morphine, Naloxone, Nitroglycerin, Norepinephrine, Olanzapine, Ondansetron, Oxytocin11

Magnesium Sulfate

Indication	Population	Dose	Route	Repeat	Standing	Source
Asthma / bronchospasm	adult	2–4 g	IV/IO	not captured	standing	pages 23, 26
Asthma / bronchospasm	peds	25 mg/kg	IV/IO	not captured	standing	pages 23, 26
Eclampsia / pre-eclampsia	adult	2–4 g	IV/IO	not captured	standing	pages 32, 39

Methylprednisolone

Indication	Population	Dose	Route	Repeat	Standing	Source
Adrenal crisis	adult	125 mg	IV/IO/IM	not captured	standing	page 15
Adrenal crisis	peds	2 mg/kg	IV/IO/IM	not captured	standing	page 15
Anaphylaxis	adult	125 mg	IV/IO/IM	not captured	standing	pages 16, 17
Anaphylaxis	peds	2 mg/kg	IV/IO/IM	not captured	standing	pages 16, 17
Asthma / bronchospasm	adult	125 mg	IV/IO/IM	not captured	standing	pages 23, 26
Asthma / bronchospasm	peds	2 mg/kg	IV/IO/IM	not captured	standing	pages 23, 26
Other	adult	125 mg	IV/IO/IM	not captured	standing	pages 23, 26
Other	peds	2 mg	IV/IO/IM	not captured	standing	pages 23, 26

Metoprolol

Indication	Population	Dose	Route	Repeat	Standing	Source
Atrial fibrillation with RVR	adult	2.5–5 mg	IV/IO	not captured	standing	page 56
Atrial fibrillation with RVR	adult	2.5–5 mg	IV/IO	not captured	standing	page 56
Other	adult	5 mg	IV	not captured	standing	page 157

Midazolam

Indication	Population	Dose	Route	Repeat	Standing	Source
Agitation	adult	10 mg	IN	not captured	standing	page 21
Agitation	adult	10 mg	IN	not captured	standing	page 21
Agitation	adult	5 mg	IV/IO/IM	not captured	standing	page 21
Agitation	adult	5 mg	IV/IO/IM	not captured	standing	page 21
Agitation	peds	0.1 mg/kg	IV/IO/IM	not captured	standing	page 21
Agitation	peds	0.1 mg/kg	IN	not captured	standing	page 21
Eclampsia / pre-eclampsia	adult	2–6 mg	IV/IO/IM	not captured	standing	page 32
Eclampsia / pre-eclampsia	adult	2–6 mg	IN	not captured	standing	page 32
Eclampsia / pre-eclampsia	adult	2–6 mg	IV/IO/IM	not captured	standing	page 32
Organophosphate poisoning	adult	10 mg	IN	not captured	standing	pages 29, 30
Organophosphate poisoning	adult	5 mg	IV/IO/IM	not captured	standing	pages 29, 30
Other	adult	0.05 mg/kg	IV/IO	not captured	standing	page 89
Other	adult	0.05 mg/kg	IV/IO	not captured	standing	page 89
Other	adult	2–6 mg	IV/IO/IM/IN	not captured	standing	page 38
Other	peds	0.05 mg/kg	IV/IO/IM/IN	not captured	standing	page 38
Other	peds	2 mg	not captured	not captured	standing	page 31
Other	peds	2.5 mg	not captured	not captured	standing	page 31
Other	peds	3 mg	not captured	not captured	standing	page 31
Other	peds	3.5 mg	not captured	not captured	standing	page 31
Other	peds	4 mg	not captured	not captured	standing	page 31
Other	peds	4.5 mg	not captured	not captured	standing	page 31
Other	peds	5 mg	not captured	not captured	standing	page 31
Seizure	adult	10 mg	IN	not captured	standing	pages 39, 40
Seizure	adult	5 mg	IV/IO/IM	not captured	standing	pages 39, 40
Seizure	peds	0.1 mg/kg	IV/IO/IM	not captured	standing	pages 39, 40
Seizure	peds	0.2 mg/kg	IN	not captured	standing	pages 39, 40
Status epilepticus	adult	5 mg	IV/IO/IM	not captured	standing	page 39

Morphine

Indication	Population	Dose	Route	Repeat	Standing	Source
Mild to moderate pain	adult	0.1 mg/kg	IV/IO/IM	not captured	standing	page 37
Mild to moderate pain	peds	0.1 mg/kg	IV/IO/IM	not captured	standing	page 37
Procedural sedation	adult	0.1 mg/kg	IV/IO/IM/SQ	not captured	standing	page 124

Naloxone

Indication	Population	Dose	Route	Repeat	Standing	Source
Opioid overdose	adult	0.4 mg	IN	not captured	standing	page 38
Opioid overdose	adult	0.4 mg	IM	not captured	standing	page 38
Opioid overdose	adult	0.4 mg	IV/IO	not captured	standing	page 38
Opioid overdose	peds	0.1 mg/kg	IN	not captured	standing	page 38
Opioid overdose	peds	0.1 mg/kg	IM	not captured	standing	page 38
Opioid overdose	peds	0.1 mg/kg	IV/IO	not captured	standing	page 38
Other	adult	0.4 mg	IM/IN	not captured	standing	page 38
Other	adult	0.4 mg	IV/IO/IM/IN	not captured	standing	page 38
Other	peds	0.1 mg/kg	IV/IO/IM/IN	not captured	standing	page 38

Nitroglycerin

Indication	Population	Dose	Route	Repeat	Standing	Source
ACS / chest pain	adult	0.4 mg	SL	not captured	standing	pages 53, 162
ACS / chest pain	adult	1 tablet	SL	not captured	standing	page 53
CHF / pulmonary edema	adult	0.4–0.8 mg	SL	not captured	standing	page 63
CHF / pulmonary edema	adult	1 inch	TOP	not captured	standing	page 63
Other	adult	0.4–0.8 mg	SL	not captured	standing	page 63
Other	adult	1 inch	TOP	not captured	standing	page 63
Other	adult	400 mcg	IV	not captured	standing	page 104

Norepinephrine

Indication	Population	Dose	Route	Repeat	Standing	Source
Hypotension / shock	adult	0.1–0.5 mcg/kg	IV/IO	not captured	standing	pages 16, 42, 44, 45, 63, 65
Hypotension / shock	peds	0.1 mcg/kg	IV/IO	not captured	standing	page 44
Hypotension / shock	peds	0.1–0.5 mcg/kg	IV/IO	not captured	standing	pages 16, 42, 44, 45, 63, 65
Sepsis	adult	0.1–0.5 mcg/kg	IV/IO	not captured	standing	pages 45, 65
Sepsis	peds	0.1–0.5 mcg/kg	IV/IO	not captured	standing	pages 45, 65

Olanzapine

Indication	Population	Dose	Route	Repeat	Standing	Source
Agitation	adult	10 mg	ODT	not captured	standing	page 21
Agitation	adult	5–10 mg	PO/ODT	not captured	standing	pages 21, 103

Ondansetron

Indication	Population	Dose	Route	Repeat	Standing	Source
Nausea / vomiting	adult	4 mg	PO/ODT	not captured	standing	page 37
Nausea / vomiting	adult	4 mg	IV/IO/IM	not captured	standing	page 37
Nausea / vomiting	peds	2 mg	PO/ODT	not captured	standing	page 37
Nausea / vomiting	peds	2 mg	IV/IO/IM	not captured	standing	page 37
Other	peds	2 mg	IV/IM/PO/ODT	not captured	standing	page 37
Other	peds	4 mg	IV/IM/PO/ODT	not captured	standing	page 37

Oxytocin

Indication	Population	Dose	Route	Repeat	Standing	Source
Obstetric hemorrhage	adult	10 mg	IM	not captured	standing	page 32
Obstetric hemorrhage	adult	20 unit	IV	not captured	standing	page 32
Other	adult	20 unit	IV	not captured	standing	page 32

P–R Packed Red Blood Cells, Pralidoxime, Racemic Epinephrine, Risperidone4

Packed Red Blood Cells

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	1 unit	IV	not captured	standing	pages 110, 111
Other	peds	10 mL/kg	IV	not captured	standing	pages 110, 111

Pralidoxime

Indication	Population	Dose	Route	Repeat	Standing	Source
Organophosphate poisoning	adult	1–2 g	IV/IO	not captured	standing	pages 29, 30
Other	adult	1 g	IV	not captured	standing	page 30
Other	adult	1200–1800 mg	IM	not captured	standing	page 30
Other	adult	600 mg	IM	not captured	standing	page 30
Other	adult	600 mg	IM	not captured	standing	page 30
Other	adult	600–1200 mg	IM	not captured	standing	page 30
Other	peds	1 g	not captured	not captured	standing	page 31
Other	peds	200–400 mg	not captured	not captured	standing	page 31
Other	peds	24–46 mg/kg	IM	not captured	standing	page 31
Other	peds	300–600 mg	not captured	not captured	standing	page 31
Other	peds	400–800 mg	not captured	not captured	standing	page 31
Other	peds	500 mg	not captured	not captured	standing	page 31
Other	peds	600 mg	not captured	not captured	standing	page 31
Other	peds	700 mg	not captured	not captured	standing	page 31
Other	peds	800 mg	not captured	not captured	standing	page 31
Other	peds	900 mg	not captured	not captured	standing	page 31

Racemic Epinephrine

Indication	Population	Dose	Route	Repeat	Standing	Source
Croup	peds	11.25 mg	NEB	not captured	standing	page 86

Risperidone

Indication	Population	Dose	Route	Repeat	Standing	Source
Agitation	adult	2 mg	PO/ODT	not captured	standing	pages 21, 103
Agitation	adult	2 mg	ODT	not captured	standing	page 21

S–Z Sodium Bicarbonate, Sodium Nitrite, Sodium Thiosulfate, Surfactant, Tetracaine, Tranexamic Acid, Whole Blood7

Sodium Bicarbonate

Indication	Population	Dose	Route	Repeat	Standing	Source
Cardiac arrest	adult	1 mEq/kg	IV/IO	not captured	standing	pages 59, 60, 61, 62
Cardiac arrest	peds	1 mEq/kg	IV/IO	not captured	standing	pages 59, 60, 61, 62
Crush injury	adult	1 mEq/kg	IV/IO	not captured	standing	pages 78, 141
Crush injury	peds	0.5–2 mEq/kg	IV/IO	not captured	standing	pages 78, 141
Hyperkalemia	adult	0.5–2 mEq/kg	IV	not captured	standing	page 142
Other	adult	0.5–1 mEq/kg	IV/IO	not captured	standing	page 38
Other	adult	0.5–2 mEq/kg	IV/IO	not captured	standing	page 141
Other	adult	0.5–2 mEq/kg	IV	not captured	standing	page 142
Other	peds	0.5–2 mEq/kg	IV/IO	not captured	standing	page 141
Other	peds	8 mL/kg	IV	not captured	standing	page 141

Sodium Nitrite

Indication	Population	Dose	Route	Repeat	Standing	Source
Cyanide poisoning	adult	10 mL	IV/IO	not captured	standing	page 38
Cyanide poisoning	peds	0.2 mL/kg	IV/IO	not captured	standing	page 38
Other	adult	10 mL	IV/IO	not captured	standing	page 38
Other	peds	0.2 mL/kg	IV/IO	not captured	standing	page 38

Sodium Thiosulfate

Indication	Population	Dose	Route	Repeat	Standing	Source
Cyanide poisoning	adult	50 mL	IV/IO	not captured	standing	page 38
Cyanide poisoning	peds	5 mL	IV/IO	not captured	standing	page 38

Surfactant

Indication	Population	Dose	Route	Repeat	Standing	Source
Anaphylaxis	adult	1 spray	IN	not captured	standing	pages 16, 17
Anaphylaxis	peds	1 spray	IN	not captured	standing	pages 16, 17
Other	peds	1 spray	IN	not captured	standing	page 17

Tetracaine

Indication	Population	Dose	Route	Repeat	Standing	Source
Mild to moderate pain	adult	1–2 drop	OPH	not captured	standing	page 73

Tranexamic Acid

Indication	Population	Dose	Route	Repeat	Standing	Source
Obstetric hemorrhage	adult	2 g	IV	not captured	standing	page 32
Obstetric hemorrhage	adult	2 g	IV	not captured	standing	page 32
Other	adult	2 g	IV	not captured	standing	pages 75, 83, 110
Other	peds	15 mg/kg	IV	not captured	standing	pages 75, 83
Trauma / hemorrhage	adult	2 g	IV	not captured	standing	pages 75, 83
Trauma / hemorrhage	peds	15 mg/kg	IV	not captured	standing	pages 75, 83

Whole Blood

Indication	Population	Dose	Route	Repeat	Standing	Source
Other	adult	1 unit	IV	not captured	standing	pages 110, 111
Other	peds	10 mL/kg	IV	not captured	standing	pages 110, 111

Massachusetts Office of Emergency Medical Services

Drugs and doses55