Contact: research@protoquiz.com

Indication

Midazolam for Agitation

143 sources122 named agencies42 statesas of 2026-10-31

Adult dosing has a median of 3.75 mg across 124 published protocols, with the middle half between 2.5 and 5.

143sources
122named agencies
42states
356entries
118named here

Includes 2 agencies outside the US.

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Adultmg

124sources
108named agencies
38states
196entries
0kept as written
minp25medianp75max
22.53.75510

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IM 24%
  • IV/IO 13%
  • IM/IN 11%
  • IV/IO/IM/IN 11%
  • IV/IM/IN 10%
  • IV/IO/IN 8%
  • IV 7%
  • IN 6%
  • IV/IM 5%
  • IV/IN 3%
  • IV/IO/IM 3%

United States EMS Protocol Census, n=124 protocols from 108 named agencies / 38 states, updated Oct 2026

Pediatric, weight-basedmg/kg

79sources
69named agencies
28states
128entries
0kept as written
minp25medianp75max
0.050.10.10.11250.3

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IM 23%
  • IV/IO 16%
  • IV/IO/IM/IN 13%
  • IV/IO/IN 13%
  • IM/IN 12%
  • IN 6%
  • IV/IM 6%
  • IV/IM/IN 5%
  • IV 4%
  • IV/IN 3%
  • IV/IO/IM 2%

United States EMS Protocol Census, n=79 protocols from 69 named agencies / 28 states, updated Oct 2026

Adult, weight-basedmg/kg

17sources
13named agencies
15states
25entries
0kept as written
minp25medianp75max
0.050.0750.10.10.2

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IO 28%
  • IM/IN 24%
  • IV/IO/IM/IN 16%
  • IM 12%
  • IV 12%
  • IV/IM 4%
  • IV/IM/IN 4%

United States EMS Protocol Census, n=17 protocols from 13 named agencies / 15 states, updated Oct 2026

Pediatricmg

6sources
4named agencies
4states
7entries
0kept as written
minp25medianp75max
12.1252.52.52.5

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IM/IN 43%
  • IM/IN 14%
  • IV 14%
  • IV/IM 14%
  • IV/IO/IM/IN 14%

United States EMS Protocol Census, n=6 protocols from 4 named agencies / 4 states, updated Oct 2026

Named agencies with a page118

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.