Midazolam for Agitation
Adult dosing has a median of 3.75 mg across 124 published protocols, with the middle half between 2.5 and 5.
Includes 2 agencies outside the US.
Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.
Adultmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 2 | 2.5 | 3.75 | 5 | 10 |
Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IM 24%
- IV/IO 13%
- IM/IN 11%
- IV/IO/IM/IN 11%
- IV/IM/IN 10%
- IV/IO/IN 8%
- IV 7%
- IN 6%
- IV/IM 5%
- IV/IN 3%
- IV/IO/IM 3%
United States EMS Protocol Census, n=124 protocols from 108 named agencies / 38 states, updated Oct 2026
Pediatric, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.05 | 0.1 | 0.1 | 0.1125 | 0.3 |
Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IM 23%
- IV/IO 16%
- IV/IO/IM/IN 13%
- IV/IO/IN 13%
- IM/IN 12%
- IN 6%
- IV/IM 6%
- IV/IM/IN 5%
- IV 4%
- IV/IN 3%
- IV/IO/IM 2%
United States EMS Protocol Census, n=79 protocols from 69 named agencies / 28 states, updated Oct 2026
Adult, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.05 | 0.075 | 0.1 | 0.1 | 0.2 |
Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IV/IO 28%
- IM/IN 24%
- IV/IO/IM/IN 16%
- IM 12%
- IV 12%
- IV/IM 4%
- IV/IM/IN 4%
United States EMS Protocol Census, n=17 protocols from 13 named agencies / 15 states, updated Oct 2026
Pediatricmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 1 | 2.125 | 2.5 | 2.5 | 2.5 |
Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IV/IM/IN 43%
- IM/IN 14%
- IV 14%
- IV/IM 14%
- IV/IO/IM/IN 14%
United States EMS Protocol Census, n=6 protocols from 4 named agencies / 4 states, updated Oct 2026
Named agencies with a page118
Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.
- Academy of Medicine of Cincinnati
- Ada County-City Emergency Services System
- Ambulance Victoria
- Anderson County Emergency Medical Services
- Arizona Department of Health Services
- Arlington EMS System
- Ashwaubenon Public Safety, Howard Fire Rescue, & De Pere Fire Rescue
- Benbrook Fire Department
- BEST EMS
- Bexar County ESD 4 Fire Rescue
- Bonner County Emergency Medical Services
- Brilliant Fire Department
- Brownsville Rural Fire District, Halsey-Shedd Fire Protection District, Jefferson Fire District, Lebanon Fire District, Scio Fire District & Sweet Home Fire & Ambulance District
- Brunswick County EMS
- Cabarrus County EMS
- Calhoun County EMS System
- Campbell County Emergency Medical Service
- Central Arizona Regional EMS
- Chelan/Douglas/Okanogan/Grant County
- City of Austin / Austin-Travis County EMS System
- Clark County EMS System
- Clark County EMS (Washington)
- County of San Diego Emergency Medical Services
- Cowlitz County EMS Council
- Craven, Jones, Pamlico Counties EMS
- Dallas Fire-Rescue
- Dane County EMS System
- Davidson County Emergency Services
- Daviess County EMS
- Department of Health Services, County of Los Angeles
- Dorchester County EMS
- Escambia County Emergency Medical Services
- Evansville Fire Department
- Fairfax County Fire and Rescue Department
- FirstHealth of the Carolinas
- Galveston Area Ambulance Authority
- Giles County EMS
- Grant County
- Greater Elgin Area EMS System
- Greenville County Emergency Medical Services
- Hays County ESD 9 EMS
- Haywood County EMS System
- Hunt County EMS
- Idaho EMS Physician Commission
- Illinois Region VIII Emergency Medical Services
- Inland Counties Emergency Medical Agency
- Kentucky Board of Emergency Medical Services
- Kern County Public Health
- La Porte County Emergency Medical Service
- Laurens County Emergency Medical Services
- Louisville Metro EMS
- Manatee County Emergency Medical Services
- Massachusetts Office of Emergency Medical Services
- McKinney Fire Department
- Mecklenburg EMS Agency
- MEP (Medical Emergency Partnership) in partnership with SSM Health
- MetroCare Services and Abilene Fire Department
- Michigan Department of Health and Human Services (MDHHS) / Midland Gladwin MCA
- Michigan Department of Health and Human Services (MDHHS) / West Michigan Regional MCC
- Ministry of Health, Emergency Health Regulatory and Accountability Branch
- Miramar Fire Rescue Department
- Montana Board of Medical Examiners
- Montgomery County Hospital District
- Mountain West Ambulance
- Nash County Emergency Medical Services
- National Emergency Medical Services
- Nebraska Medicine Division of Prehospital and Emergency Medical Services
- Nevada EMS Program
- New Hampshire Bureau of Emergency Medical Services
- New Jersey Department of Health
- New Mexico EMS Bureau
- New York State Department of Health, Bureau of Emergency Medical Services and Trauma Systems
- North Carolina Office of Emergency Medical Services (NC OEMS)
- North Central Oregon EMS Agencies
- Northeastern Montana Stat Air Ambulance Cooperative
- Northwest Community EMS System
- Northwest Region Emergency Medical Services & Trauma Care Council
- Ocala/Marion County/The Villages Public Safety EMS
- OCEMS
- Office of the EMS Medical Director for Kansas City, Missouri
- Oklahoma State Department of Health
- Old Dominion EMS Alliance, Inc.
- Osage Ambulance District
- Pend Oreille County Emergency Medical Services
- Peninsulas EMS Council, Inc.
- Pennsylvania Department of Health, Bureau of Emergency Medical Services
- Peoria Area EMS System
- Pettis County Ambulance District
- Rappahannock EMS Council
- Region 4 EMS
- Region One Metropolitan Ambulance Council
- Region One Metropolitan Ambulance Council (MAC)
- Region X EMS
- REMSA
- REMSA Sioux Falls
- Reno County Emergency Medical Services
- Rhode Island Department of Health – Center for Emergency Medical Services
- Richland County Emergency Medical Services
- Routt County EMS
- Rowan County Emergency Services EMS Division
- Salt Lake County EMS
- Santa Barbara County Public Health Department
- Santa Cruz County EMS Agency
- Southern Fox Valley EMS System
- Stanly County EMS
- State of Hawaiʻi Department of Health, Emergency Medical Services & Injury Prevention System Branch
- State of Nebraska
- Susquehanna Regional EMS
- Tennessee Emergency Medical Services
- The Williamson County EMS System
- Three Rivers Ambulance Authority & Fort Wayne Fire Department
- Tidewater Emergency Medical Services Council, Inc.
- UNM EMS Consortium
- Utah Department of Public Safety, Bureau of Emergency Medical Services
- UTSW/Parkland BioTel EMS System
- Virgin Islands Fire & Emergency Medical Services
- Weber County Paramedic Program
- West Virginia Department of Health, Office of Emergency Medical Services