Indication

Naloxone for Opioid overdose

188 sources155 named agencies47 statesas of 2026-10-31

Adult dosing has a median of 0.8 mg across 185 published protocols, with the middle half between 0.4 and 1.5.

188sources

155named agencies

47states

661entries

153named here

Includes 3 agencies outside the US.

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Adultmg

185sources

153named agencies

46states

345entries

0kept as written

min	p25	median	p75	max
0.4	0.4	0.8	1.5	2

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IN 25%
IV/IO/IM/IN 12%
IV/IO 11%
IM 9%
IV 9%
IM/IN 8%
IV/IO/IM 6%
IV/IM/IN 5%
IV/IO/IM/IN/ET 3%
IV/IM 2%
IV/IM/SQ 1%
IV/IO/IN 1%
NEB 1%
IM/SQ 1%
IO 1%
IV/IO/IM/IN/NEB 1%
SQ 1%
ET 0%
IM/SQ/ET 0%
IV/IM/IN/ET 0%
IV/IM/IN/SQ 0%
IV/IN 0%
IV/IO/ET 0%
IV/IO/IM/IN/SL/ET 0%
IV/IO/IM/IN/SQ 0%
IV/IO/IM/IN/SQ/ET 0%
IV/IO/IM/SQ 0%

United States EMS Protocol Census, n=185 protocols from 153 named agencies / 46 states, updated Oct 2026

Pediatric, weight-basedmg/kg

137sources

119named agencies

40states

244entries

0kept as written

min	p25	median	p75	max
0.1	0.1	0.1	0.1	0.15

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IN 22%
IV/IO 14%
IV/IO/IM/IN 11%
IM/IN 10%
IV/IO/IM 8%
IV 7%
IM 7%
IV/IM 5%
IV/IM/IN 4%
IV/IO/IM/IN/ET 3%
IV/IO/IM/IN/NEB 1%
IV/IO/IN 1%
ET 1%
IM/SQ 1%
IV/IM/SQ 1%
NEB 1%
IM/SQ/ET 0%
IO 0%
IV/IM/IN/ET 0%
IV/IM/IN/SQ 0%
IV/IO/ET 0%
IV/IO/IM/IN/SL/ET 0%
IV/IO/IM/IN/SQ 0%
IV/IO/IM/SQ 0%
IV/IO/IM/SQ/ET 0%

United States EMS Protocol Census, n=137 protocols from 119 named agencies / 40 states, updated Oct 2026

Pediatricmg

48sources

41named agencies

25states

66entries

0kept as written

min	p25	median	p75	max
0.4	0.5	1	2	2

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IN 39%
IV/IO/IM/IN 18%
IV/IO 11%
IM 8%
IV/IM/IN 8%
IM/IN 6%
IV 3%
NEB 3%
IV/IO/IM/IN/SQ/ET 2%
IV/IO/IN 2%
SQ 2%

United States EMS Protocol Census, n=48 protocols from 41 named agencies / 25 states, updated Oct 2026

Adult, weight-basedmg/kg

3sources

3named agencies

3states

5entries

0kept as written

Below 5 sources, so no distribution is published for this group — only the counts above.

Routes

IN 40%
IV/IM/IN 20%
IV/IO 20%
IV/IO/IM/IN/ET 20%

United States EMS Protocol Census, n=3 protocols from 3 named agencies / 3 states, updated Oct 2026

PediatricmL

1sources

1named agencies

1states

1entries

0kept as written

Below 5 sources, so no distribution is published for this group — only the counts above.

Routes

IN 100%

United States EMS Protocol Census, n=1 protocols from 1 named agencies / 1 states, updated Oct 2026

Named agencies with a page153

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.