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Medication

Methylprednisolone in US EMS protocols

160protocols
134named agencies
42states and regions
14indications
857dose entries
100% of 857machine-parsed

Includes 1 agency outside the US.

IndicationSpread: box is the middle half, dot means most agreeRange
Adrenal crisis AdultMost use 125 mg range 60 to 125 mg, n=40
Pediatric, weight-basedMost use 2 mg/kg matches NASEMSO range 1 to 2 mg/kg, n=35
Allergic reaction AdultAll use 125 mg n=54
Pediatric, weight-basedMost use 2 mg/kg range 1 to 2 mg/kg, n=49
Anaphylaxis AdultMost use 125 mg range 62.5 to 125 mg, n=73
Adult, weight-based1 to 2 mg/kg median 2, n=8
Pediatric, weight-basedMost use 2 mg/kg range 1 to 2 mg/kg, n=67
Asthma / bronchospasm AdultMost use 125 mg range 60 to 125 mg, n=87
Adult, weight-basedMost use 2 mg/kg range 1 to 2 mg/kg, n=7
Pediatric, weight-basedMost use 2 mg/kg matches NASEMSO range 1 to 2 mg/kg, n=90
COPD AdultAll use 125 mg n=32
Pediatric, weight-basedAll use 2 mg/kg n=13
Croup Pediatric, weight-based1 to 2 mg/kg median 2, n=7
Other AdultMost use 125 mg range 60 to 125 mg, n=60
Adult, weight-based1 to 2 mg/kg median 2, n=5
Pediatric, weight-basedMost use 2 mg/kg range 1 to 2 mg/kg, n=56
Respiratory distress AdultMost use 125 mg range 62.5 to 125 mg, n=29
Pediatric, weight-basedMost use 2 mg/kg matches NASEMSO range 1 to 2 mg/kg, n=28

Too few protocols to chart yet (protocols in brackets): Burns (1), Cardiac arrest (1), CHF / pulmonary edema (1), Hypotension / shock (6), Sepsis (2), Stridor (3)

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Named agencies with a page132

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Cite this

United States EMS Protocol Census, Methylprednisolone: n=160 protocols from 134 named agencies / 42 states, as of 2026-10-31

MethodologyData licenseStudy your own protocol in the app

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.