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Indication

Methylprednisolone for Anaphylaxis

81 sources66 named agencies34 statesas of 2026-10-31

Adult dosing has a median of 125 mg across 73 published protocols, with the middle half between 125 and 125.

81sources
66named agencies
34states
151entries
65named here

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Adultmg

73sources
60named agencies
31states
73entries
0kept as written
minp25medianp75max
62.5125125125125

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IO 32%
  • IV/IO/IM 32%
  • IV 25%
  • IV/IM 11%
  • IV/IO/IM/PO 1%

United States EMS Protocol Census, n=73 protocols from 60 named agencies / 31 states, updated Oct 2026

Pediatric, weight-basedmg/kg

67sources
55named agencies
31states
69entries
0kept as written
minp25medianp75max
12222

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IO 30%
  • IV/IO/IM 30%
  • IV 22%
  • IV/IM 16%
  • IV/IO/IM/PO 1%

United States EMS Protocol Census, n=67 protocols from 55 named agencies / 31 states, updated Oct 2026

Adult, weight-basedmg/kg

8sources
6named agencies
7states
9entries
0kept as written
minp25medianp75max
11222

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IM 44%
  • IV 22%
  • IV/IO 22%

United States EMS Protocol Census, n=8 protocols from 6 named agencies / 7 states, updated Oct 2026

Named agencies with a page65

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.