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Medication

Fentanyl in US EMS protocols

230protocols
192named agencies
51states and regions
21indications
1,226dose entries
100% of 1,226machine-parsed

Includes 4 agencies outside the US.

IndicationSpread: box is the middle half, dot means most agreeRange
ACS / chest pain Adult0.025 to 0.05 mg median 0.025, n=29
Adult, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.0025 mg/kg, n=22
Pediatric, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.001 mg/kg, n=13
Burns Adult0.025 to 0.05 mg median 0.0375, n=6
Pediatric, weight-based0.0005 to 0.002 mg/kg median 0.001, n=8
Other Adult0.025 to 0.1 mg median 0.05, n=57
Adult, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=60
Pediatric, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=67
Mild to moderate pain Adult0.025 to 0.1 mg median 0.05, n=91
Adult, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.0023 mg/kg, n=92
Pediatric, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=157
Severe pain Adult0.025 to 0.05 mg median 0.05, n=19
Adult, weight-basedMost use 0.001 mg/kg matches NASEMSO range 0.0005 to 0.002 mg/kg, n=26
Pediatric, weight-basedMost use 0.001 mg/kg matches NASEMSO range 0.0005 to 0.002 mg/kg, n=44
Post-intubation sedation Adult0.025 to 0.1 mg median 0.05, n=21
Adult, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=26
Pediatric, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=26
Procedural sedation Adult0.025 to 0.1 mg median 0.05, n=24
Adult, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.001 mg/kg, n=20
Pediatric, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=26
RSI induction Adult0.025 to 0.1 mg median 0.05, n=7
Adult, weight-based0.0005 to 0.003 mg/kg median 0.001, n=20
Pediatric, weight-basedMost use 0.001 mg/kg range 0.0005 to 0.002 mg/kg, n=15

Too few protocols to chart yet (protocols in brackets): Atrial fibrillation with RVR (1), Agitation (4), Bradycardia (2), Cardiac arrest (3), CHF / pulmonary edema (3), Crush injury (2), Nausea / vomiting (1), Post-ROSC care (3), STEMI (3), SVT (1), Narrow-complex tachycardia (1), Wide-complex tachycardia (1), Trauma / hemorrhage (3)

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Named agencies with a page188

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Cite this

United States EMS Protocol Census, Fentanyl: n=230 protocols from 192 named agencies / 51 states, as of 2026-10-31

MethodologyData licenseStudy your own protocol in the app

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.