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Medication

Epinephrine in US EMS protocols

237protocols
199named agencies
52states and regions
26indications
2,144dose entries
100% of 2,144machine-parsed

Includes 4 agencies outside the US.

IndicationSpread: box is the middle half, dot means most agreeRange
Allergic reaction AdultMost use 0.3 mg range 0.25 to 0.5 mg, n=26
PediatricAll use 0.15 mg n=9
Pediatric, weight-basedAll use 0.01 mg/kg n=17
Anaphylaxis AdultMost use 0.3 mg matches NASEMSO range 0.1 to 0.5 mg, n=199
Adult0.3 to 1 mL median 0.5, n=7
Adult, weight-basedAll use 0.01 mg/kg matches WAO n=5
PediatricMost use 0.15 mg range 0.15 to 0.3 mg, n=69
Pediatric, weight-basedMost use 0.01 mg/kg matches WAO range 0.01 to 0.02 mg/kg, n=128
Asthma / bronchospasm AdultMost use 0.3 mg range 0.1 to 0.5 mg, n=98
Adult, weight-basedAll use 0.01 mg/kg n=5
PediatricMost use 0.15 mg range 0.15 to 0.3 mg, n=16
Pediatric, weight-basedMost use 0.01 mg/kg range 0.01 to 0.02 mg/kg, n=80
Asystole / PEA AdultMost use 1 mg matches AHA 2025 range 0.5 to 1 mg, n=7
Bradycardia AdultMost use 0.002 mg range 0.001 to 0.006 mg, n=81
Adult0.5 to 1 mL median 0.5, n=6
PediatricMost use 0.01 mg range 0.005 to 0.01 mg, n=6
Pediatric, weight-basedMost use 0.01 mg/kg matches AHA 2025 range 0.01 to 0.02 mg/kg, n=117
Cardiac arrest AdultMost use 1 mg matches AHA 2025 range 0.5 to 2 mg, n=198
Adult, weight-basedAll use 0.01 mg/kg n=5
Pediatric, weight-basedMost use 0.01 mg/kg matches AHA 2025 range 0.01 to 0.02 mg/kg, n=191
Cardiogenic shock AdultMost use 0.01 mg range 0.005 to 0.02 mg, n=5
CHF / pulmonary edema Adult0.002 to 0.01 mg median 0.005, n=5
Croup Adult1 to 3 mg median 1, n=5
Pediatric1 to 5 mg median 3, n=29
Pediatric2.5 to 5 mL median 5, n=11
Pediatric, weight-basedAll use 0.5 mg/kg n=5
Pediatric, weight-basedMost use 0.5 mL/kg range 0.5 to 1 mL/kg, n=5
Hypotension / shock Adult0.005 to 0.02 mg median 0.01, n=61
Adult0.5 to 1 mL median 1, n=15
Adult, weight-basedMost use 0.0001 mg/kg range 0.0001 to 0.0001 mg/kg, n=5
Pediatric0.005 to 0.01 mg median 0.01, n=9
Pediatric, weight-based0.0001 to 0.0002 mg/kg median 0.0001, n=30
Neonatal resuscitation Pediatric, weight-basedMost use 0.01 mg/kg range 0.01 to 0.02 mg/kg, n=18
Other AdultMost use 0.3 mg range 0.1 to 0.6 mg, n=56
Adult0.5 to 3 mL median 1, n=15
Adult, weight-based0.0001 to 0.0001 mg/kg median 0.0001, n=9
Pediatric0.1 to 0.5 mg median 0.15, n=26
Pediatric0.5 to 3 mL median 1.75, n=14
Pediatric, weight-basedMost use 0.01 mg/kg range 0.0075 to 0.02 mg/kg, n=61
Pediatric, weight-basedMost use 0.1 mL/kg range 0.05 to 0.1 mL/kg, n=8
Post-ROSC care AdultMost use 0.01 mg range 0.008 to 0.01 mg, n=5
Respiratory distress AdultMost use 0.3 mg range 0.3 to 0.5 mg, n=29
Pediatric0.5 to 1 mg median 1, n=5
Pediatric, weight-basedAll use 0.01 mg/kg n=13
Sepsis AdultMost use 0.01 mg range 0.005 to 0.01 mg, n=6
Pediatric, weight-based0.0001 to 0.0001 mg/kg median 0.0001, n=6
Stridor Adult1 to 5 mg median 2, n=13
AdultMost use 5 mL range 2.5 to 5 mL, n=9
Pediatric1 to 5 mg median 2, n=16
Pediatric2.5 to 5 mL median 5, n=13

Too few protocols to chart yet (protocols in brackets): Beta-blocker / calcium-channel-blocker overdose (1), Burns (1), COPD (3), Cyanide poisoning (2), Head injury / TBI (1), Hypothermia (1), RSI induction (4), Trauma / hemorrhage (4), Traumatic arrest (1), VF / pulseless VT (4)

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Named agencies with a page193

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Cite this

United States EMS Protocol Census, Epinephrine: n=237 protocols from 199 named agencies / 52 states, as of 2026-10-31

MethodologyData licenseStudy your own protocol in the app

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.