Diphenhydramine for Dystonic reaction
Adult dosing has a median of 37.5 mg across 123 published protocols, with the middle half between 25 and 50.
Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.
Adultmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 12.5 | 25 | 37.5 | 50 | 50 |
Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IV/IO/IM 35%
- IV/IM 35%
- IV 10%
- IV/IO/IM/PO 7%
- IM 4%
- IV/IM/PO 4%
- IV/IO 4%
- PO 2%
United States EMS Protocol Census, n=123 protocols from 106 named agencies / 40 states, updated Oct 2026
Pediatric, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.5 | 1 | 1 | 1 | 1.5 |
Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IV/IO/IM 38%
- IV/IM 35%
- IV/IO/IM/PO 10%
- IV 9%
- IV/IM/PO 4%
- IM 3%
- IV/IO 1%
- PO 1%
United States EMS Protocol Census, n=104 protocols from 88 named agencies / 36 states, updated Oct 2026
Adult, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 1 | 1 | 1 | 1 | 1 |
Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IV/IM 50%
- IV/IO/IM 20%
- IV/IO/IM/PO 20%
- IV/IO 10%
United States EMS Protocol Census, n=9 protocols from 8 named agencies / 8 states, updated Oct 2026
Pediatricmg
Below 5 sources, so no distribution is published for this group — only the counts above.
Routes
- IV 100%
United States EMS Protocol Census, n=1 protocols from 0 named agencies / 1 states, updated Oct 2026
Named agencies with a page110
Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.
- Ada County-City Emergency Services System
- Anderson County Emergency Medical Services
- Arlington EMS System
- Ashwaubenon Public Safety, Howard Fire Rescue, & De Pere Fire Rescue
- Aurora Fire Rescue
- Berkeley County EMS
- Berrien County Medical Control Authority
- BEST EMS
- Bexar County ESD 4 Fire Rescue
- Brilliant Fire Department
- Brownsville Rural Fire District, Halsey-Shedd Fire Protection District, Jefferson Fire District, Lebanon Fire District, Scio Fire District & Sweet Home Fire & Ambulance District
- Brunswick County EMS
- Cabarrus County EMS
- Charleston County EMS
- Chelan/Douglas/Okanogan/Grant County
- Clark County EMS System
- Clark County EMS (Washington)
- Confederated Tribes of Grand Ronde Department of Emergency Services
- Coos County Emergency Medical Services
- County of San Diego Emergency Medical Services
- Craven, Jones, Pamlico Counties EMS
- Dallas Fire-Rescue
- DC Fire and EMS
- Denver Health Paramedic Division
- Department of Health Services, County of Los Angeles
- Dorchester County EMS
- East Baton Rouge Parish Department of Emergency Medical Services
- El Campo Emergency Medical Service
- Escambia County Emergency Medical Services
- Evansville Fire Department
- Fairfax County Fire and Rescue Department
- Fern Creek Fire and Emergency Medical Services
- FirstHealth of the Carolinas
- Fort Lauderdale Fire Rescue
- Fort Worth Regional EMS System
- Franklin County Emergency Medical Services
- Galveston Area Ambulance Authority
- Giles County EMS
- Greater Elgin Area EMS System
- Hays County ESD 9 EMS
- Houston Fire Department
- Hunt County EMS
- Kentucky Board of Emergency Medical Services
- Kern County Public Health
- Kosciusko County Paramedics
- Lake County Emergency Medical System
- Lake Emergency Medical System
- Laurens County Emergency Medical Services
- Levy County Department of Public Safety
- Louisville Metro EMS
- Maine Emergency Medical Services
- Maryland Institute for Emergency Medical Services Systems
- McKinney Fire Department
- Mecklenburg EMS Agency
- MEP (Medical Emergency Partnership) in partnership with SSM Health
- MetroCare Services and Abilene Fire Department
- Michigan Department of Health and Human Services (MDHHS) / Midland Gladwin MCA
- Michigan Department of Health and Human Services (MDHHS) / West Michigan Regional MCC
- Miramar Fire Rescue Department
- Montgomery County Hospital District
- Muskegon County
- Nash County Emergency Medical Services
- National Emergency Medical Services
- Nebraska Medicine Division of Prehospital and Emergency Medical Services
- Nevada EMS Program
- New Hampshire Bureau of Emergency Medical Services
- New Jersey Department of Health
- New York State Department of Health, Bureau of Emergency Medical Services and Trauma Systems
- North Carolina Office of Emergency Medical Services (NC OEMS)
- Northeast Ohio Regional EMS Protocol Committee
- Northeastern Montana Stat Air Ambulance Cooperative
- Northwest Community EMS System
- Norton Sound Health Corporation
- Nueces County ESD4
- Oakland County Medical Control Authority
- OCEMS
- Oklahoma State Department of Health
- Old Dominion EMS Alliance, Inc.
- Palm Beach Gardens Fire Rescue
- Pend Oreille County Emergency Medical Services
- Peoria Area EMS System
- Platte Valley Ambulance Service
- Rappahannock EMS Council
- Regional Emergency Medical Advisory Committee of New York City
- REMSA
- REMSA Sioux Falls
- Reno County Emergency Medical Services
- Rhode Island Department of Health – Center for Emergency Medical Services
- Routt County EMS
- Rowan County Emergency Services EMS Division
- Salem Fire Department
- Santa Barbara County Public Health Department
- Santa Cruz County EMS Agency
- Sierra – Sacramento Valley EMS Agency
- Stanly County EMS
- State of Nebraska
- Stevens County Emergency Medical Services
- Susquehanna Regional EMS
- Tennessee Emergency Medical Services
- The Williamson County EMS System
- Thurston County Medic One
- Tidewater Emergency Medical Services Council, Inc.
- Tri-County Emergency Medical Control Authority
- Tri County Emergency Medical Services, Inc.
- UNM EMS Consortium
- Vermont Department of Health
- Virgin Islands Fire & Emergency Medical Services
- Washington State Department of Health
- West Virginia Department of Health, Office of Emergency Medical Services
- Wilson County ESD #4