Ketamine for Agitation
Adult weight-based dosing has a median of 2.75 mg/kg across 78 published protocols, with the middle half between 2 and 4.
Includes 2 agencies outside the US.
Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.
Adult, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 1 | 2 | 2.75 | 4 | 5 |
Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IM 54%
- IV/IO 19%
- IV 12%
- IM/IN 5%
- IV/IO/IN 4%
- IV/IM 3%
- IV/IM/IN 2%
- IN 1%
- IV/IN 1%
- IV/IO/IM/IN 1%
United States EMS Protocol Census, n=78 protocols from 65 named agencies / 35 states, updated Oct 2026
Pediatric, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 1 | 1.5 | 2 | 3 | 4 |
Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IM 46%
- IV/IO 22%
- IV 13%
- IM/IN 7%
- IV/IM 4%
- IN 2%
- IV/IM/IN 2%
- IV/IO/IM/IN 2%
- IV/IO/IN 2%
United States EMS Protocol Census, n=35 protocols from 28 named agencies / 19 states, updated Oct 2026
Adultmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 100 | 250 | 250 | 300 | 300 |
Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.
Routes
- IM 92%
- IV/IM 8%
United States EMS Protocol Census, n=13 protocols from 9 named agencies / 8 states, updated Oct 2026
Pediatricmg
Below 5 sources, so no distribution is published for this group — only the counts above.
Routes
- IM 67%
- IV/IO/IN 33%
United States EMS Protocol Census, n=3 protocols from 2 named agencies / 3 states, updated Oct 2026
Named agencies with a page72
Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.
- Academy of Medicine of Cincinnati
- Adams, Benton, Franklin, Yakima Counties
- Alabama Department of Public Health Office of Emergency Medical Services
- Ambulance Victoria
- Anderson County Emergency Medical Services
- Arizona Department of Health Services
- Arlington EMS System
- Ashwaubenon Public Safety, Howard Fire Rescue, & De Pere Fire Rescue
- BEST EMS
- Bexar County ESD 4 Fire Rescue
- Brilliant Fire Department
- Brownsville Rural Fire District, Halsey-Shedd Fire Protection District, Jefferson Fire District, Lebanon Fire District, Scio Fire District & Sweet Home Fire & Ambulance District
- Calhoun County EMS System
- Campbell County Emergency Medical Service
- Charleston County EMS
- Chelan/Douglas/Okanogan/Grant County
- Clark County EMS System
- Coos County Emergency Medical Services
- Dane County EMS System
- Daviess County EMS
- East Baton Rouge Parish Department of Emergency Medical Services
- Evansville Fire Department
- Fairfax County Fire and Rescue Department
- Fort Lauderdale Fire Rescue
- Galveston Area Ambulance Authority
- Grant County
- Idaho EMS Physician Commission
- Kosciusko County Paramedics
- La Porte County Emergency Medical Service
- Laurens County Emergency Medical Services
- Manatee County Emergency Medical Services
- Maryland Institute for Emergency Medical Services Systems
- Massachusetts Office of Emergency Medical Services
- McKinney Fire Department
- MEP (Medical Emergency Partnership) in partnership with SSM Health
- MetroCare Services and Abilene Fire Department
- Michigan Department of Health and Human Services (MDHHS) / Midland Gladwin MCA
- Ministry of Health, Emergency Health Regulatory and Accountability Branch
- Miramar Fire Rescue Department
- Mountain West Ambulance
- Nebraska Medicine Division of Prehospital and Emergency Medical Services
- Nevada EMS Program
- New Jersey Department of Health
- New York State Department of Health, Bureau of Emergency Medical Services and Trauma Systems
- North Central Oregon EMS Agencies
- Northeastern Montana Stat Air Ambulance Cooperative
- Ocala/Marion County/The Villages Public Safety EMS
- Pend Oreille County Emergency Medical Services
- Peninsulas EMS Council, Inc.
- Pennsylvania Department of Health, Bureau of Emergency Medical Services
- Peoria Area EMS System
- Rappahannock EMS Council
- Region 1 Emergency Medical Services
- Region One Metropolitan Ambulance Council (MAC)
- Region X EMS
- REMSA
- REMSA Sioux Falls
- Reno County Emergency Medical Services
- Rhode Island Department of Health – Center for Emergency Medical Services
- Salt Lake County EMS
- South Carolina Department of Public Health (DPH) Division of EMS
- Southern Fox Valley EMS System
- State of Nebraska
- Stevens County Emergency Medical Services
- Susquehanna Regional EMS
- Tennessee Emergency Medical Services
- The Williamson County EMS System
- Tippecanoe Emergency Ambulance Service
- Utah Department of Public Safety, Bureau of Emergency Medical Services
- UTSW/Parkland BioTel EMS System
- Vermont Department of Health
- West Virginia Department of Health, Office of Emergency Medical Services