Indication

Diphenhydramine for Other

114 sources97 named agencies43 statesas of 2026-10-31

Adult dosing has a median of 25 mg across 99 published protocols, with the middle half between 25 and 50.

114sources

97named agencies

43states

377entries

94named here

Includes 2 agencies outside the US.

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Adultmg

99sources

85named agencies

38states

182entries

0kept as written

min	p25	median	p75	max
11.25	25	25	50	50

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IV/IM 32%
IV/IO/IM 27%
IV 13%
PO 9%
IM 6%
IV/IO 6%
IV/IO/IM/PO 4%
IV/IM/PO 3%
IV/PO 1%

United States EMS Protocol Census, n=99 protocols from 85 named agencies / 38 states, updated Oct 2026

Pediatric, weight-basedmg/kg

89sources

76named agencies

36states

154entries

0kept as written

min	p25	median	p75	max
0.5	1	1	1	1.5

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IV/IM 32%
IV/IO/IM 32%
IV 8%
IM 6%
IV/IO/IM/PO 6%
IV/IM/PO 5%
IV/IO 4%
PO 4%
IO 1%
IV/PO 1%

United States EMS Protocol Census, n=89 protocols from 76 named agencies / 36 states, updated Oct 2026

Adult, weight-basedmg/kg

15sources

12named agencies

11states

20entries

0kept as written

min	p25	median	p75	max
0.5	1	1	1	1

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IV/IM 45%
IV/IM/PO 25%
IV 15%
IV/IO/IM 15%

United States EMS Protocol Census, n=15 protocols from 12 named agencies / 11 states, updated Oct 2026

Pediatricmg

8sources

8named agencies

8states

21entries

0kept as written

min	p25	median	p75	max
12.5	18.75	23.75	25	50

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

IV/IM 67%
PO 24%
IV 5%
IV/IO/PO 5%

United States EMS Protocol Census, n=8 protocols from 8 named agencies / 8 states, updated Oct 2026

Named agencies with a page94

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.