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Indication

Sodium Thiosulfate for Cyanide poisoning

20 sources18 named agencies14 statesas of 2026-10-31

Adult dosing has a median of 12500 mg across 14 published protocols, with the middle half between 12500 and 12500.

20sources
18named agencies
14states
40entries
18named here

Includes 1 agency outside the US.

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Adultmg

14sources
12named agencies
11states
14entries
0kept as written
minp25medianp75max
1250012500125001250012500

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV 57%
  • IV/IO 43%

United States EMS Protocol Census, n=14 protocols from 12 named agencies / 11 states, updated Oct 2026

Pediatric, weight-basedmL/kg

9sources
8named agencies
6states
10entries
0kept as written
minp25medianp75max
11.61.651.652

Values in mL/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV 60%
  • IV/IO 40%

United States EMS Protocol Census, n=9 protocols from 8 named agencies / 6 states, updated Oct 2026

Pediatric, weight-basedmg/kg

7sources
6named agencies
5states
7entries
0kept as written
minp25medianp75max
250250250325500

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV 57%
  • IV/IO 43%

United States EMS Protocol Census, n=7 protocols from 6 named agencies / 5 states, updated Oct 2026

AdultmL

6sources
6named agencies
3states
7entries
0kept as written
minp25medianp75max
5050505050

Values in mL. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV 57%
  • IV/IO 43%

United States EMS Protocol Census, n=6 protocols from 6 named agencies / 3 states, updated Oct 2026

Adult, weight-basedmL/kg

1sources
1named agencies
1states
1entries
0kept as written

Below 5 sources, so no distribution is published for this group — only the counts above.

Routes

  • IV 100%

United States EMS Protocol Census, n=1 protocols from 1 named agencies / 1 states, updated Oct 2026

PediatricmL

1sources
1named agencies
1states
1entries
0kept as written

Below 5 sources, so no distribution is published for this group — only the counts above.

Routes

  • IV/IO 100%

United States EMS Protocol Census, n=1 protocols from 1 named agencies / 1 states, updated Oct 2026

Named agencies with a page18

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.