Contact: research@protoquiz.com

Indication

Diphenhydramine for Anaphylaxis

93 sources74 named agencies37 statesas of 2026-10-31

Pediatric weight-based dosing has a median of 1 mg/kg across 87 published protocols, with the middle half between 1 and 1.

93sources
74named agencies
37states
217entries
73named here

Includes 1 agency outside the US.

Doses far off from what other protocols give are likely misreads, so they are left out until checked. How that works.

Pediatric, weight-basedmg/kg

87sources
69named agencies
36states
105entries
0kept as written
minp25medianp75max
0.51112

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IO/IM 40%
  • IV/IM 23%
  • IM 9%
  • IV 9%
  • IV/IM/PO 7%
  • PO 7%
  • IV/IO 5%
  • IV/IO/IM/PO 2%

United States EMS Protocol Census, n=87 protocols from 69 named agencies / 36 states, updated Oct 2026

Adultmg

84sources
67named agencies
34states
104entries
0kept as written
minp25medianp75max
12.52537.55050

Values in mg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IO/IM 39%
  • IV/IM 20%
  • IM 11%
  • IV 11%
  • PO 8%
  • IV/IO 6%
  • IV/IM/PO 5%
  • IV/IO/IM/PO 2%

United States EMS Protocol Census, n=84 protocols from 67 named agencies / 34 states, updated Oct 2026

Adult, weight-basedmg/kg

8sources
6named agencies
6states
8entries
0kept as written
minp25medianp75max
11111

Values in mg/kg. One value per source (that source's median), so a document listing a medication five times still gets one vote.

Routes

  • IV/IM 50%
  • IV/IM/PO 25%
  • IV/IO/IM 25%

United States EMS Protocol Census, n=8 protocols from 6 named agencies / 6 states, updated Oct 2026

Named agencies with a page73

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

Training reference compiled from published protocols. Not a clinical order. Verify with your agency and medical director.