:root{
  --ground:oklch(0.99 0.003 250);
  --panel:oklch(0.965 0.006 250);
  --ink:oklch(0.22 0.015 260);
  --muted:oklch(0.47 0.02 260);
  --rule:oklch(0.87 0.008 260);
  --accent:oklch(0.52 0.19 27);
  --link:oklch(0.42 0.11 255);
  --sig-current:oklch(0.52 0.13 150);
  --sig-review:oklch(0.66 0.15 75);
  --r:6px;
  --sans:"IBM Plex Sans",-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif;
  --mono:"IBM Plex Mono",ui-monospace,SFMono-Regular,monospace;
}
*{box-sizing:border-box}
body{margin:0;background:var(--ground);color:var(--ink);font-family:var(--sans);font-size:1rem;line-height:1.6;-webkit-font-smoothing:antialiased;text-rendering:optimizeLegibility}
a{color:var(--link);text-decoration:underline;text-underline-offset:2px;text-decoration-thickness:1px}
a:hover{text-decoration-thickness:2px}
:focus-visible{outline:2px solid var(--accent);outline-offset:2px;border-radius:2px}
[hidden]{display:none!important}
.wrap{max-width:1120px;margin:0 auto;padding:0 24px}

/* The site header is shared chrome (assets/chrome.css). Census owns everything BELOW
   the header, starting at the research bar. */

main{padding:14px 0 32px}
.crumbs{font-size:.8125rem;color:var(--muted);margin:0 0 12px}
.crumbs a{color:var(--muted);text-decoration:none}
.crumbs a:hover{color:var(--link);text-decoration:underline}
.crumbs .sep{margin:0 6px;opacity:.6}

.layout{display:grid;grid-template-columns:minmax(0,1fr) 300px;gap:48px;align-items:start}
.layout.solo{grid-template-columns:minmax(0,1fr)}
.col{min-width:0}
.rail{min-width:0;display:flex;flex-direction:column;gap:16px;position:sticky;top:16px}

/* document header */
.dochead{border-bottom:1px solid var(--rule);padding-bottom:12px;margin-bottom:14px}
.badge{display:block;font-size:.8125rem;font-weight:500;color:var(--muted);margin:0 0 2px}
h1{font-size:1.625rem;line-height:1.25;margin:0 0 6px;font-weight:600;letter-spacing:-.015em}
.meta{display:flex;flex-wrap:wrap;gap:6px;margin:8px 0 0}
.chip,.pill{display:inline-block;border:1px solid var(--rule);border-radius:var(--r);padding:1px 8px;font-size:.8125rem;line-height:1.5;color:var(--muted);background:var(--panel);font-variant-numeric:tabular-nums}
.pill{font-weight:500;background:transparent}
.sig-current{color:var(--sig-current);border-color:color-mix(in oklch,var(--sig-current) 40%,var(--rule))}
.sig-review{color:oklch(0.48 0.13 75);border-color:color-mix(in oklch,var(--sig-review) 50%,var(--rule))}
.sig-superseded{color:var(--muted)}

h2{font-size:1.125rem;line-height:1.35;margin:24px 0 10px;font-weight:600;letter-spacing:-.01em;display:flex;align-items:baseline;gap:8px;flex-wrap:wrap}
h3{font-size:1rem;margin:18px 0 6px;font-weight:600;color:var(--ink)}
h4{font-size:.875rem;margin:12px 0 4px;font-weight:600;color:var(--ink)}
.count{font-family:var(--mono);font-size:.75rem;font-weight:400;color:var(--muted);background:var(--panel);border:1px solid var(--rule);border-radius:999px;padding:0 7px;margin-left:6px;font-variant-numeric:tabular-nums}
h2 .unit{font-family:var(--mono);font-size:.875rem;font-weight:400;color:var(--muted)}
p{margin:0 0 10px;max-width:72ch}
.lede{font-size:1rem;color:var(--muted);margin:6px 0 0;max-width:72ch}
.honest,.cite{font-size:.875rem;color:var(--muted)}

/* one dense line of counts: the landing scale line and the page stats */
.summary{display:flex;flex-wrap:wrap;align-items:baseline;gap:2px 10px;margin:0 0 12px;font-size:.9375rem;color:var(--muted);max-width:none}
.summary .n{font-family:var(--mono);font-weight:500;color:var(--ink);font-variant-numeric:tabular-nums}
.summary .sep{width:1px;align-self:stretch;background:var(--rule);margin:2px 2px}
.stats{display:flex;flex-wrap:wrap;gap:2px 16px;margin:0 0 14px;font-size:.875rem;color:var(--muted)}
.stat .v{font-family:var(--mono);font-weight:500;color:var(--ink);font-variant-numeric:tabular-nums;margin-right:4px}

.warn{background:oklch(0.975 0.035 85);border:1px solid oklch(0.86 0.075 80);border-radius:var(--r);padding:8px 12px;font-size:.9375rem;margin:0 0 12px;max-width:72ch}

/* the landing tool: title, counts, one search box beside the findings carousel */
.tool{margin:0 0 14px}
.tool.has-slides{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,440px);gap:16px 48px;align-items:start}
.tool .slides{margin:0}
.tool .filter{margin-top:16px}
.chips{display:flex;flex-wrap:wrap;align-items:center;gap:6px;margin:0 0 8px}
.chips .muted{margin-right:4px}
.chips a{font-size:.8125rem;padding:4px 10px;border:1px solid var(--rule);border-radius:999px;background:var(--ground);color:var(--ink);text-decoration:none}
.chips a:hover{border-color:var(--muted)}
/* the States tab: the map beside the list */
.statemap{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,1fr);gap:12px 32px;align-items:start}
.statemap ul.stategrid{columns:2}
.usmap-fig{margin:0}
.usmap{display:block;width:100%;height:auto}
.usmap .s{stroke:var(--ground);stroke-width:.9}
.usmap a .s{cursor:pointer}
.usmap a:hover .s{fill:var(--link)}
.usmap .r0,.legend .r0{fill:var(--panel);background:var(--panel)}
.usmap .r1,.legend .r1{fill:oklch(0.92 0.03 27);background:oklch(0.92 0.03 27)}
.usmap .r2,.legend .r2{fill:oklch(0.83 0.07 27);background:oklch(0.83 0.07 27)}
.usmap .r3,.legend .r3{fill:oklch(0.66 0.15 27);background:oklch(0.66 0.15 27)}
.usmap .r4,.legend .r4{fill:oklch(0.48 0.17 27);background:oklch(0.48 0.17 27)}
.usmap .named{stroke:var(--ink);stroke-width:1.6;stroke-linejoin:round}
.legend{display:flex;flex-wrap:wrap;gap:4px 12px;margin:6px 0 0;font-size:.75rem;color:var(--muted)}
.legend i{display:inline-block;width:11px;height:11px;border-radius:2px;margin-right:5px;vertical-align:-1px;border:1px solid var(--rule)}
.legend .named{background:none;border:2px solid var(--ink)}
.tool h1{margin:0 0 4px}
.filter{display:block;width:100%;max-width:560px;font:inherit;font-size:1rem;padding:9px 12px;border:1px solid var(--rule);border-radius:var(--r);background:var(--ground);color:var(--ink);margin:0 0 12px}
.filter:focus-visible{outline:2px solid var(--accent);outline-offset:1px;border-color:var(--accent)}
.tabnav{display:flex;gap:20px;border-bottom:1px solid var(--rule);margin:0 0 12px;overflow-x:auto}
.tabnav a{padding:6px 0;font-weight:500;font-size:.9375rem;color:var(--muted);text-decoration:none;border-bottom:2px solid transparent;margin-bottom:-1px;white-space:nowrap}
.tabnav a[aria-selected=true]{color:var(--ink);border-bottom-color:var(--accent)}
/* No JS: :target picks the tab, Drugs by default. JS: data-tab picks it, and a
   search shows every tab that has a hit. */
.tabs:not(.js) section{display:none}
.tabs:not(.js) section:target,.tabs:not(.js):not(:has(section:target)) section:first-of-type{display:block}
.tabs.js section{display:none}
.tabs.js[data-tab=drugs] #drugs,.tabs.js[data-tab=states] #states,.tabs.js[data-tab=agencies] #agencies,.tabs.js.searching section{display:block}
.tabs.js:not(.searching) section>h2{display:none}
.tabs section>h2{margin-top:8px}
.tabs.searching .tabnav{display:none}

/* compact link columns; long names clip to one line and keep their title */
ul.cols{list-style:none;padding:0;margin:0 0 10px;columns:3;column-gap:20px}
ul.cols li{break-inside:avoid;padding:1px 0;font-size:.875rem;line-height:1.5}
ul.cols.four{columns:4}
ul.cols.six{columns:6}
ul.cols.four li,ul.cols.six li{white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
ul.cols a{text-decoration:none}
ul.cols a:hover{text-decoration:underline}
/* long landing lists show their first rows; "Show all" (JS only) opens the rest */
.more{display:none;font:inherit;font-size:.875rem;font-weight:500;color:var(--link);background:var(--panel);border:1px solid var(--rule);border-radius:var(--r);padding:4px 12px;cursor:pointer;margin:2px 0 8px}
.tabs.js:not(.searching) .more{display:inline-block}
.tabs.js:not(.searching) ul.six.clip:not(.all)>li:nth-child(n+61),.tabs.js:not(.searching) ul.four.clip:not(.all)>li:nth-child(n+41){display:none}
ul.stategrid{columns:5}
ul.stategrid li{display:flex;justify-content:space-between;gap:8px}
ul.stategrid .count{margin:0;border:0;background:none;padding:0}
ul.inline{list-style:none;padding:0;margin:0 0 12px;display:flex;flex-wrap:wrap;gap:6px}
ul.inline li{background:var(--panel);border:1px solid var(--rule);border-radius:var(--r);padding:2px 10px;font-size:.875rem;font-variant-numeric:tabular-nums}
ul.results{list-style:none;padding:0;margin:0;border-top:1px solid var(--rule)}
ul.results li{display:flex;align-items:baseline;justify-content:space-between;gap:16px;padding:6px 4px;border-bottom:1px solid var(--rule)}

/* folds: one line until opened */
details.fold{border-top:1px solid var(--rule)}
details.fold>summary{cursor:pointer;padding:7px 2px;font-size:.9375rem;font-weight:500;display:flex;align-items:baseline;gap:8px;min-width:0}
details.fold>summary{list-style:none}
details.fold>summary::-webkit-details-marker{display:none}
details.fold>summary::before{content:"\25B8";color:var(--muted);transition:transform .15s}
details.fold[open]>summary::before{transform:rotate(90deg)}
.actions details.fold>summary::before{content:none}
details.fold>summary .names{flex:1;min-width:0;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-weight:400;font-size:.8125rem;color:var(--muted)}
details.fold[open]>summary{margin-bottom:6px}
#doses details.fold:last-of-type{border-bottom:1px solid var(--rule)}
.drug h3{margin:12px 0 4px}

/* the bottom row: small links, plus folds that open to full width */
.actions{display:flex;flex-wrap:wrap;align-items:baseline;gap:4px 20px;margin:20px 0 8px;padding-top:10px;border-top:1px solid var(--rule);font-size:.875rem}
.actions details.fold{border:0}
.actions details.fold>summary{padding:0;font-size:.875rem;color:var(--link);font-weight:400}
.actions details.fold[open]{flex-basis:100%;padding:8px 0}
.actions details.fold[open]>summary{margin-bottom:8px}
.actions>a{white-space:nowrap}

/* the drug page: one row per distribution, a /research box plot beside the digits */
table.spread{min-width:0;width:100%}
table.spread th{white-space:normal}
table.spread th[scope=row]{font-weight:500;background:none;white-space:normal;color:var(--ink);font-size:.875rem}
table.spread tr.cont th,table.spread tr.cont td{border-top:0}
table.spread th[scope=row],table.spread td{vertical-align:middle;padding:3px 10px;line-height:1.4}
table.spread td:nth-child(2){width:140px}
.rng{white-space:nowrap;font-family:var(--mono);font-size:.8125rem}
.rng .muted{font-family:var(--sans);margin-left:6px}
.rng .gl{font-family:var(--sans);font-size:.75rem;color:var(--muted);margin-left:6px;white-space:nowrap}
.rng .gl:hover{color:var(--link)}
.box{display:block;width:120px;height:15px;overflow:visible}
.box .w{stroke:#0072B2;stroke-width:1.5;fill:none}
.box rect{fill:#E69F00;stroke:#0072B2;stroke-width:1.5}
.box .m{stroke:#0b2a4a;stroke-width:2.5}
.box .agree{fill:#E69F00;stroke:#0b2a4a;stroke-width:1.5}
.also{font-size:.875rem;color:var(--muted);max-width:none;margin:10px 0}

/* dense hairline tables, mono numerals */
.scroll{overflow-x:auto;overscroll-behavior-x:contain;border:1px solid var(--rule);border-radius:var(--r);margin:0 0 10px}
table{min-width:100%;border-collapse:collapse;font-size:.875rem;font-variant-numeric:tabular-nums}
th{text-align:left;font-weight:600;color:var(--muted);background:var(--panel);border-bottom:1px solid var(--rule);padding:6px 10px;white-space:nowrap;font-size:.8125rem}
td{padding:5px 10px;border-bottom:1px solid var(--rule);vertical-align:top}
tbody th{border-bottom:1px solid var(--rule)}
tbody tr:last-child td,tbody tr:last-child th{border-bottom:0}
tbody tr:hover{background:var(--panel)}
table.dose td:nth-child(n+3),table.coverage td:nth-child(n+2){font-family:var(--mono)}
table.dose td:nth-child(3){white-space:nowrap}
td.src{font-family:var(--sans);white-space:nowrap}
.src,.muted{color:var(--muted);font-size:.8125rem}
.raw{font-family:var(--mono);font-size:.8125rem}

/* rail panels (methodology, license, indication pages) */
.panel{border:1px solid var(--rule);border-radius:var(--r);padding:12px 14px;background:var(--ground)}
.panel h2{font-size:.9375rem;margin:0 0 8px;font-weight:600}
.panel p{font-size:.875rem;margin:0 0 10px;max-width:none}
ul.railnav{list-style:none;padding:0;margin:0;font-size:.875rem}
ul.railnav li{padding:4px 0;border-bottom:1px solid var(--rule)}
ul.railnav li:last-child{border-bottom:0}
ul.railnav a{text-decoration:none}
ul.railnav a:hover{text-decoration:underline}
.toc{position:sticky;top:16px}
.toc ul{list-style:none;padding:0;margin:0;font-size:.875rem}
.toc li{padding:3px 0}
.toc a{text-decoration:none;color:var(--muted)}
.toc a:hover{color:var(--link);text-decoration:underline}
.rail details.fold{border:1px solid var(--rule);border-radius:var(--r);padding:0 12px}

/* cite this */
.citebox{border:1px solid var(--rule);border-radius:var(--r);background:var(--panel);padding:8px 12px;margin:0 0 8px;max-width:72ch}
.citebox .cite{font-family:var(--mono);font-size:.8125rem;line-height:1.55;color:var(--ink);margin:0;word-break:break-word}
.citebox .cite+.cite{margin-top:6px}
.copybtn{font:inherit;font-size:.875rem;font-weight:500;color:var(--ink);background:var(--panel);border:1px solid var(--rule);border-radius:var(--r);padding:4px 12px;cursor:pointer}
.copybtn:hover{background:oklch(0.94 0.008 250)}
.copybtn.ok{color:var(--sig-current);border-color:color-mix(in oklch,var(--sig-current) 45%,var(--rule))}

/* the five-number range bar on indication pages */
.five{margin:0 0 14px}
.five-track{position:relative;height:10px;background:var(--panel);border:1px solid var(--rule);border-radius:var(--r);margin:12px 0 4px}
.five-iqr{position:absolute;top:-1px;bottom:-1px;background:color-mix(in oklch,var(--accent) 22%,var(--ground));border:1px solid color-mix(in oklch,var(--accent) 55%,var(--rule));border-radius:3px}
.five-med{position:absolute;top:-5px;bottom:-5px;width:2px;background:var(--accent);border-radius:1px}
.five-ends{display:flex;justify-content:space-between;font-family:var(--mono);font-size:.75rem;color:var(--muted);font-variant-numeric:tabular-nums;margin:0 0 8px}
.five-nums{min-width:0;width:auto;font-size:.8125rem}
.five-nums th{background:transparent;border-bottom:1px solid var(--rule);padding:4px 16px 4px 0;font-weight:500}
.five-nums td{font-family:var(--mono);padding:4px 16px 4px 0;border-bottom:0}
.five-nums tbody tr:hover{background:transparent}
.hist{min-width:0}
.hist th{width:160px;font-family:var(--mono);color:var(--ink);background:transparent;border:0;padding:4px 12px 4px 0;font-weight:400}
.hist td{border:0;padding:4px 0}
.hist .n{width:56px;text-align:right;color:var(--muted);font-family:var(--mono)}
.hist tbody tr:hover{background:transparent}
.bar{display:block;height:10px;background:var(--accent);border-radius:2px;min-width:2px}

/* the one request link: a button to /research/request/ */
.bigbtn{display:inline-block;font-weight:600;font-size:.9375rem;padding:8px 16px;border-radius:var(--r);background:#0072B2;color:#fff;text-decoration:none}
.bigbtn:hover{background:#005f94;text-decoration:none}
.request{margin:0 0 10px;display:flex;flex-wrap:wrap;align-items:center;gap:6px 12px}
.contact{border:1px solid var(--rule);border-radius:var(--r);padding:12px 16px;background:var(--panel);margin:0 0 8px}
.contact h2{margin-top:0}

/* The site footer is shared chrome (assets/chrome.css); census only styles the
   one-line disclaimer that sits above it. */
.census-disclaimer{border-top:1px solid var(--rule);padding:10px 0;background:var(--panel)}
.census-disclaimer p{max-width:none}
.disclaimer{margin:0;color:var(--muted);font-size:.8125rem}

@media(max-width:960px){
  .layout{grid-template-columns:minmax(0,1fr);gap:24px}
  .rail,.toc{position:static}
  ul.cols{columns:2}
  ul.cols.four{columns:2}
  ul.cols.six,ul.stategrid{columns:3}
  .tool.has-slides,.statemap{grid-template-columns:minmax(0,1fr)}
}
@media(max-width:640px){
  .wrap{padding:0 16px}
  ul.cols,ul.cols.four{columns:1}
  ul.cols.six,ul.stategrid,.statemap ul.stategrid{columns:2}
  .tabs.js:not(.searching) ul.six.clip:not(.all)>li:nth-child(n+31),.tabs.js:not(.searching) ul.four.clip:not(.all)>li:nth-child(n+21){display:none}
  h1{font-size:1.375rem}
  table.spread td:nth-child(2){width:84px}
  table.spread th[scope=row],table.spread td{padding:3px 6px;overflow-wrap:anywhere}
  .box{width:76px}
  .rng{white-space:normal}
  .rng .muted{display:block;margin:0}
  .rng .muted+.gl{display:block;margin:0}
}
.shead{margin:6px 0 22px}
.seye{display:flex;gap:10px;flex-wrap:wrap;font:500 .72rem/1 "IBM Plex Mono",ui-monospace,monospace;letter-spacing:.14em;text-transform:uppercase;color:var(--muted);margin-bottom:14px}
.seye a{color:inherit;text-decoration:none}
.seye a:hover{color:var(--link)}
.shead h1{font-size:clamp(2.4rem,6vw,3.6rem);line-height:1;letter-spacing:-.035em;font-weight:700;margin:0 0 10px}
.slede{max-width:760px;font-size:1.1rem;line-height:1.5;color:var(--muted);margin:0 0 18px}
.sbar{height:26px;border-radius:5px;background:var(--panel);overflow:hidden}
.sbar i{display:block;height:100%;background:#0072b2}
.skey{display:flex;gap:22px;flex-wrap:wrap;margin-top:8px;font-size:.85rem;color:var(--muted)}
.sfind{margin:0 0 18px}
.sfind input{width:100%;max-width:360px;box-sizing:border-box;font:inherit;padding:9px 12px;border:1px solid var(--rule);border-radius:6px;background:#fff;color:var(--ink)}
.sfind-none{margin:10px 0 0;color:var(--muted)}
@media(prefers-reduced-motion:reduce){*{animation:none!important;transition:none!important;scroll-behavior:auto!important}}